Organizations that need to implement NIST 800-53 are primarily federal agencies and contractors who manage federal information systems. This includes any organization that processes, stores, or transmits federal information. Additionally, entities providing services to federal agencies, such as cloud service providers and third-party vendors, must adhere to the NIST 800-53 guidelines to ensure the security and privacy of federal information systems.

A GRC Assessment Platform like Isora assists organizations in developing and maintaining an information security risk management program that aligns with NIST 800-53. Utilizing Isora, organizations can inventory their IT assets, applications, third-party vendors, organizational units, and personnel, creating a detailed overview essential for safeguarding federal information systems. The platform supports continuous risk self-assessments, crucial for aligning with NIST 800-53 standards. Risks identified are tracked in a risk register, allowing for prioritized mitigation and follow-up. This structured approach not only aids in achieving compliance with NIST 800-53 but also enhances the organization’s overall security and privacy posture.