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HIPAA Security Rule Compliance Software

The GRC Assessment Platform™ for HIPAA Security Rule compliance

Isora GRC gives healthcare organizations one connected workspace to operationalize the HIPAA Security Rule, with risk assessments across administrative, physical, and technical safeguards, connected ePHI system and business associate inventories, risk tracking and documented remediation, and the structured documentation an OCR investigation requires, all in one place.

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Problem

HIPAA Security Rule evidence is scattered

Documenting HIPAA Security Rule compliance is difficult when the risk assessment lives in a spreadsheet and the ePHI inventory and business associate reviews are maintained separately. Tracing a finding from assessment through remediation to current status can take days.

Solution

One platform for the HIPAA Security Rule compliance lifecycle
Isora GRC brings the workflows the Security Rule requires into one connected workspace, with risk assessments across administrative, physical, and technical safeguards, ePHI inventory management, business associate oversight, and reporting. Findings reach the risk register as assessments surface them, so the documentation OCR expects is built as the work happens.
Assessment Management
Assess administrative, physical, and technical safeguards

Group HIPAA assessments into a recurring series and target every department, system, and business associate that handles ePHI, covering §164.308 (administrative), §164.310 (physical), and §164.312 (technical). Completion and scoring update in one dashboard, reminders handle the follow-up, and findings reach the risk register with lineage back to the safeguard and the system.

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Inventory Management
Maintain an inventory of every system that handles ePHI

Track every system, application, and vendor that stores, processes, or transmits ePHI, with each record linked to its risk assessments, associated risks, data classification, and business associate relationships. When OCR asks which systems handle ePHI and what controls protect them, the answer is already in the inventory.

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Questionnaires & Surveys
Document the security practices behind every business associate agreement

Distribute questionnaires from a prebuilt library that covers HIPAA alongside NIST, CIS, GLBA, and HECVAT, and link results to each vendor record alongside risk ratings and BAA documentation. Multiple contributors can answer a single questionnaire and attach evidence inline, so every relationship carries a documented assessment history rather than a signed agreement alone.

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Reports & Scorecards
Produce the evidence trail an OCR investigation asks for

Scorecards pull from live assessment data, risk register entries, and vendor records to show assessment completion, safeguard implementation status, remediation progress, and ePHI inventory coverage. Drill down from any score to the individual response and the evidence behind it, and export to PDF or CSV. The risk register keeps an append-only audit log, so the record of what was found and fixed stays time-stamped.

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See the GRC Assessment Platform in action
Isora GRC is the GRC Assessment Platform™ that gives security teams one connected workspace to run assessments, manage vendors and assets, track risks, and prove compliance.
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Latest Content
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Frequently Asked Questions
HIPAA Security Rule Compliance Software FAQs
Find the answers you need here, or chat with us.
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What does the HIPAA Security Rule require?

The Security Rule (45 CFR Part 164, Subpart C) requires covered entities and business associates to implement administrative, physical, and technical safeguards for ePHI. This includes risk assessments, access controls, data integrity protections, audit controls, transmission security, and workforce training. The 2025 HIPAA Security Rule NPRM proposes additional requirements for encryption, MFA, and vulnerability management. Isora provides the assessment, risk tracking, inventory, and reporting workflows to operationalize these requirements.

How does Isora help with HIPAA risk assessments?

Isora includes prebuilt questionnaires covering HIPAA, aligned to the three safeguard categories (§164.308, §164.310, §164.312). Teams assess across ePHI systems, departments, and business associates. Evidence is collected inline and linked to the responses it supports. Findings flow directly into the risk register with full lineage from assessment to risk to remediation.

Can Isora manage business associate oversight?

Yes. Isora maintains a centralized business associate inventory with linked questionnaires, assessment results, risk ratings, and BAA documentation. Teams can track which BAs access ePHI, when they were last assessed, and what their current security posture is, which is the documented oversight OCR enforcement actions consistently look for.

How does HIPAA compliance software differ from general GRC tools?

Isora is purpose-built for information security teams, with the assessments, risk registers, inventories, and compliance reporting HIPAA practitioners work in every day. Isora deploys in weeks with no-code setup, minimal IT lift, and no outside consultants.

Can Isora manage HIPAA alongside HITRUST, NIST, and other frameworks?

HITRUST r2 assessment results can serve as evidence of Recognized Security Practices under the 2021 HITECH Act amendment (Pub. L. 116-321). HHS OCR may consider these when determining enforcement outcomes, and HITRUST certification remains separate from a formal safe harbor for HIPAA violations. Isora supports both HIPAA and HITRUST assessments in the same workspace, so evidence serves both frameworks.

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